Hormonal Breakout Cream: illustrative photo of a pharmacy jar
The Hormonal Breakout Cream jar in an everyday setting
Hormonal Breakout Cream at a glance: what it does and how you use it. A custom formula with azelaic acid, clindamycin and topical spironolactone, compounded for you by a licensed pharmacy. Apply a thin layer to clean, dry skin as directed, usually at night. Start slowly if your skin is sensitive.
A hand holding the Hormonal Breakout Cream jar, shown at real size
Close-up of the Hormonal Breakout Cream jar

Images are for illustration only. Your medication is prepared and packaged by a licensed pharmacy, so containers, labels and colors will look different.

Skin

Hormonal Breakout Cream

Compounded cream · azelaic acid, clindamycin & spironolactone

$79/mo · $79 billed monthly

Or split it into smaller payments withKlarna.

For breakouts that follow your hormones around, especially along the jaw and chin.

Plan: billed only after a clinician approves you

✓ Free assessment · pay only if prescribed

Start your free assessment
Licensed clinicians
Free, discreet shipping
All-in price
Your care team, on callText or email anytime, reply within 24 hours. Call 9 a.m. to 8 p.m. ET.
Product details

A custom formula with azelaic acid, clindamycin and topical spironolactone, compounded for you by a licensed pharmacy.

  • Once a day
  • Made for you
  • Monthly refills
  • Reviewed by a licensed U.S. clinician
  • Free, discreet shipping
Key ingredients
  • Azelaic acid
  • Clindamycin
  • Topical spironolactone
How to use it
Apply a thin layer to clean, dry skin as directed, usually at night. Start slowly if your skin is sensitive.
What's included
  • A licensed clinician's review of your health history
  • Medication, if prescribed
  • Monthly check-ins, and dose adjustments when appropriate
  • A care team you can text or email, with a response within 24 hours, or call from 9 a.m. to 8 p.m. ET
  • Refill reminders and easy plan changes
  • Goddess Protocol Plus app membership (coming soon)
Side effects & safety
Mild dryness, redness or tingling is common in the first weeks. Avoid if pregnant or planning pregnancy unless your clinician says otherwise. Use sunscreen daily. Your clinician reviews your skin, photos and history first.

Based on published research and prescribing information: American Academy of Dermatology: acne guidelines (2024) · SAFA trial of spironolactone for adult women with acne (BMJ, 2023). Your clinician reviews your personal risks before prescribing.

About compounded medications
This is a compounded medication, so it isn't FDA-approved. Your clinician can talk you through FDA-approved alternatives.

Prescription required. A licensed clinician decides whether treatment is appropriate, and which medication and dose, if any, is right for you. Exploring options doesn't mean you'll be prescribed. Results vary. Plans renew automatically; cancel anytime at least 48 hours before your next billing date. Prepaid plans are refunded for unused months.

What's inside

For us, ingredients matter

Compounded for you by a licensed pharmacy. Here's what each ingredient is there to do.

Wild grasses on a cream background

Azelaic acid

Calms redness and breakouts and helps fade dark marks. Found naturally in grains like barley and wheat.

A single dewdrop falling from a leaf

Clindamycin

A topical antibiotic that targets acne bacteria. Paired with other actives to help prevent resistance.

A pink magnolia flower

Topical spironolactone

Blocks androgen activity right at the skin, aimed at hormone-driven breakouts. Newer and less studied than the tablet.

Midlife skin

Your skin is changing. So is your routine.

Start your free assessment ›

How to use

How to use it. Simple, every time.

Apply a thin layer to clean, dry skin as directed, usually at night. Start slowly if your skin is sensitive.

How care works ›

Feel good. Feel supported.

01.

Licensed clinicians

A clinician builds a formula around your skin.

02.

Rooted in research

Ingredients with real evidence behind them.

03.

Made for midlife skin

Hormonal breakouts, redness and dark spots, all welcome here.

What to expect

Change that builds over time.

  1. Weeks 1–4

    The adjustment phase

    Some dryness, flaking or a few extra breakouts can happen as skin adjusts. Start slow and moisturize.

  2. Weeks 8–12

    Early changes

    In studies, skin changes usually take two to three months to show. Monthly photos help you see them.

  3. Month 3+

    Review and refine

    Your clinician checks in and adjusts the formula or strength if needed.

Timelines are based on these studies. Results vary, and your clinician will tailor the plan to you.

  1. Thiboutot D et al. Efficacy and safety of azelaic acid 15% gel as a new treatment for papulopustular rosacea. J Am Acad Dermatol. 2003;48(6):836-845
  2. Weiss JS et al. Topical tretinoin improves photoaged skin. JAMA. 1988;259(4):527-532
Check-ins every month

Us vs. the usual

Real care. No shortcuts.

Not a rushed seven-minute appointment, and not guessing on your own. Ongoing care from people who get midlife.

Goddess Protocol RxA rushed appointmentGoing it alone
A licensed clinician reviews your history✓✓
Care focused on midlife women✓
Monthly check-ins and dose adjustments✓
Text your care team anytime✓
All-in price, nothing owed unless prescribed✓✓
App, recipes and workouts included✓

Included with every plan

Everything you need, in one place

Clinician review

A licensed U.S. clinician reviews your health history.

Monthly check-ins

Dose adjustments when appropriate, and refill reminders.

Free shipping

Discreet delivery to your door.

Plus app included

Hespera (your private AI chat), workouts, recipes and sleep stories. Coming soon.

Straight talk, in your inbox

Research, real stories and one manageable next step. Unsubscribe anytime.

Hormonal Breakout Cream$79/mo · Monthly
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