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Ivermectin

Ingredient · In our Redness Relief Formula

Ivermectin, applied to the skin

Ivermectin cream is an FDA-approved rosacea treatment that calms the inflamed bumps of rosacea. A Cochrane review rated the evidence behind it as high quality.1,2

Close-up of a young green seedling growing in textured soil, symbolic soil-origin imagery
Ivermectin

Photos are illustrations, not the medicine. Ivermectin is made in a lab.

FDA-approved ingredient

Ivermectin 1% cream is FDA-approved for the inflammatory bumps of rosacea.1 Ours is combined with other actives. Our creams are compounded by a licensed pharmacy, and compounded versions are not FDA-approved.4

FDA-approved for this useWell studied, used off-labelEarly evidenceLittle or no human data

The studies below used FDA-approved products or other forms. Our compounded version hasn't been studied in trials, and results may differ.

What it is

Ivermectin is best known as an anti-parasitic medicine. As a cream, it's used for the red bumps and pimples of rosacea.1

Why it's in this product

In our Redness Relief Formula, ivermectin works alongside azelaic acid, metronidazole and niacinamide, so the cream comes at rosacea from more than one angle.

Redness Relief Formula

What the studies in people show

  • Systematic reviewHigh-quality evidenceA Cochrane review rated the evidence for ivermectin cream as high quality. In two trials, people using it were nearly twice as likely as those on placebo to say their rosacea improved.2
  • Randomized trialEdged out metronidazoleIn 962 people with rosacea, ivermectin 1% cream reduced inflamed bumps by 83% at 16 weeks, versus 74% with metronidazole 0.75% cream. Side effects were similar.3

What we don't know yet

Rosacea trials usually last a few months, and how long results last after stopping isn't well reported.2 Our combination cream hasn't been tested as a whole.

Safety, in plain English

Side effects were uncommon in trials: burning and skin irritation in about 1% of people or fewer.1

A licensed clinician reviews your health history and decides whether this cream is appropriate for you. Exploring it here never means you'll get a prescription.

Curious about ivermectin?

Start with a free assessment. A licensed clinician reviews your health history and decides whether treatment is appropriate. No pressure, and no prescription unless it makes sense for you.

See Redness Relief FormulaHow care works

Sources

  1. U.S. National Library of Medicine, DailyMed. Soolantra (ivermectin) cream, 1%: prescribing information. DailyMed
  2. van Zuuren EJ, et al. Interventions for rosacea. Cochrane Database Syst Rev. 2015;(4):CD003262. PubMed 25919144
  3. Taieb A, et al. Superiority of ivermectin 1% cream over metronidazole 0.75% cream in treating inflammatory lesions of rosacea: a randomized, investigator-blinded trial. Br J Dermatol. 2015;172:1103-1110. PubMed 25228137
  4. U.S. Food and Drug Administration. Compounding and the FDA: Questions and Answers. FDA

Sources checked November 8, 2026. This page is general education, not medical advice, and it doesn't mean any treatment is right for you. Photos: Unsplash (Robert Anderson).