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Estradiol Gel
Estradiol · transdermal gel · 3-month supply
Coming soon
A quick-drying daily gel, rubbed into the skin. Another skin-delivered estrogen option, if a pill isn't your thing.
We're finalizing this option with our pharmacy partner. You can start your assessment now, and your clinician will talk through what's available.
Not prescribed? You pay nothing.
Product details
Estradiol gel is absorbed through the skin, giving a steady dose of estrogen without a pill.
- Once a day
- Dries quickly
- 3-month supply
- Reviewed by a licensed U.S. clinician
- Free, discreet shipping
How to use it
What's included
- A licensed clinician's review of your health history
- Medication, if prescribed
- Monthly check-ins, and dose adjustments when appropriate
- A care team you can text or email, with a response within 24 hours, or call from 9 a.m. to 8 p.m. ET
- Refill reminders and easy plan changes
- Goddess Protocol Plus app membership (coming soon)
Side effects & safety
Based on published research and prescribing information: The Menopause Society: 2022 Hormone Therapy Position Statement. Your clinician reviews your personal risks before prescribing.
Often discussed together
Your clinician decides whether any combination is right for you.
Prescription required. A licensed clinician decides whether treatment is appropriate, and which medication and dose, if any, is right for you. Exploring options doesn't mean you'll be prescribed. Results vary. Plans renew automatically; cancel anytime at least 48 hours before your next billing date. Prepaid plans are refunded for unused months.
How to use
How to use it. Simple, every time.
Pump the prescribed amount onto clean skin, usually the arm or thigh, and let it dry. Wash your hands afterward.
How care works ›Feel good. Feel supported.
Licensed clinicians
Menopause-literate care from real U.S. clinicians.
Rooted in research
Built on The Menopause Society's guidance, explained in plain English.
Whole-woman support
Sleep, mood, strength and the rest of your very full life.
What to expect
Change that builds over time.
- Weeks 1–2
Settling in
Your body adjusts to the new routine. Mild breast tenderness, spotting or bloating can happen early and often eases. Message your care team anytime.
- Weeks 4–8
Early changes
Many women in studies notice hot flashes and sleep shifting within the first couple of months. Everyone's timeline is different.
- Month 3
Check in and adjust
Your clinician reviews how you're feeling and whether the dose or form still fits.
Timelines are based on these studies. Results vary, and your clinician will tailor the plan to you.
Check-ins every month
Us vs. the usual
Real care. No shortcuts.
Not a rushed seven-minute appointment, and not guessing on your own. Ongoing care from people who get midlife.
| Goddess Protocol Rx | A rushed appointment | Going it alone | |
|---|---|---|---|
| A licensed clinician reviews your history | ✓ | ✓ | |
| Care focused on midlife women | ✓ | ||
| Monthly check-ins and dose adjustments | ✓ | ||
| Text your care team anytime | ✓ | ||
| All-in price, nothing owed unless prescribed | ✓ | ✓ | |
| App, recipes and workouts included | ✓ |
Included with every plan
Everything you need, in one place
Clinician review
A licensed U.S. clinician reviews your health history.
Monthly check-ins
Dose adjustments when appropriate, and refill reminders.
Free shipping
Discreet delivery to your door.
Plus app included
Hespera (your private AI chat), workouts, recipes and sleep stories. Coming soon.
3-month supply
3-month supplyStraight talk, in your inbox
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